Ocular gene therapy as a sustained drug delivery system: pharmacokinetic and genokinetic perspectives

Leferman Carmen-Ecaterina et al.
2025
Issue 11
pp 984 - 993
DOI: JMedLife-18-984

Ocular pharmacotherapy is constrained by compartmental anatomy and clearance barriers that limit sustained posterior-segment exposure. Intravitreal bolus dosing, therefore, remains dominant for retinal disease but produces...

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