2014, Volume 7, Issue Spec Iss 3, pp 133 – 136

Use of benzodiazepines and detoxification with methadone

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Authors and Affiliations

Correspondence to:FCarolina Negrei, Lecturer, MD, PhD, Department of Toxicology, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, code 020956, Bucharest, Romania, Mobile phone: +40 726160275, Fax: +40213111152, E-mail: carol_n2002@hotmail.com

Abstract

Rationale: Benzodiazepines are used as anti anxiety drugs, as well as in adjunct treatment for a range of neurological and psychiatric disorders. Abusive patterns of use were increasingly reported and building evidence points to prevalence of benzodiazepines abuse, on one hand as well as to their common abuse in combination with other drugs such as opioids, most frequently.

Objective: The main objective of this research is to conduct a systematic study on the behavior profile of a patient admitted to a prison hospital, who is a benzodiazepines user consecutive to admission into a methadone administration program.

Methods and results: Statistic values have been taken into account describing the distribution and the distribution form of the various variables studied to find the normality degree of distributions, regarding three measurements at the three moments: before the administration of methadone, immediately after its completion and two months after completion.

Conclusions and discussions: The statistic results obtained speak of a strong positive correlation, allowing the support of the fact that persons diagnosed with prescribed/ unprescribed benzodiazepine, use the display association with the admission into a methadone administration program, based on the assumption which concerns a significant positive association between the use of reported benzodiazepine and the administration of methadone in the questioned patients on admission.

As far as the second premise regarding the administration of methadone is concerned it brings about an improvement in the level of benzodiazepines used in research patients, which one may assert that, according to the results obtained, the initiation of methadone therapy in the detoxification program is conducive to the reduction of benzodiazepines use.

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About this article

PMC ID: 4391402
PubMed ID: 25870711
DOI: 

Article Publishing Date (print): 2014
Available Online: 

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


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