2023, Volume 16, Issue 8, pp 1178 – 1182

A comparative study to assess the use of chromium in type 2 diabetes mellitus

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Authors and Affiliations

Corresponding Author: Fatima Alkhalidi Department of Community Medicine, College of Medicine, University of Al-Qadisiyah, AL-Qadisiyah, Iraq Email: fatima.alkhalidi@qu.edu.iq

Abstract

Diabetes mellitus is a prevalent endocrine disorder characterized by elevated blood glucose levels, often resulting in complications affecting multiple organs, such as retinopathy, nephropathy, and neuropathy. Among potential interventions, certain micronutrients, like chromium, have the potential to improve glycemic management. The potential of chromium to mitigate insulin resistance and enhance insulin sensitivity through cellular receptors underscores its significance. Conversely, insufficient dietary chromium intake could contribute to diabetes development. This research aimed to evaluate the impact of chromium supplementation among individuals with diabetes. In a single-blind randomized clinical trial, participants aged 40 to 60 years with uncontrolled diabetes were divided into two groups. The intervention group received a daily chromium supplement of 200 mcg and their regular diabetes medication regimen, while the control group received only medication. The follow-up period spanned four months, during which fasting blood sugar, HbA1c levels, and lipid profiles were assessed for both groups, followed by a comparative analysis. Patients had a mean age of 52.3±6.3 years. Males constituted only 47.5% of participants, and women were 52.5%. The initial HbA1c level at the start of the study for individuals receiving chromium was 10.4±2.4. Following the follow-up period, the average HbA1c level decreased significantly to 7.2±1.7, showing a statistically significant difference. Furthermore, there was a significant reduction in the mean fasting blood sugar levels, approaching normal levels. These results suggest a beneficial role of chromium supplementation in managing type 2 diabetes mellitus, contributing to improved glycemic control.

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About this article

PMC ID: 10652672
PubMed ID: 
DOI: 10.25122/jml-2023-0081

Article Publishing Date (print): 8 2023
Available Online: 

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


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