Acute microbiologically negative hypoxic interstitial pneumonia on HAART: Immune Reconstitution Inflammatory Syndrome unmasking Pneumocystis Jiroveci infection with an atypical presentation • JML Journal of Medicine and Life

2012, Volume 5, Issue 2, pp 189 – 191

Acute microbiologically negative hypoxic interstitial pneumonia on HAART: Immune Reconstitution Inflammatory Syndrome unmasking Pneumocystis Jiroveci infection with an atypical presentation

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Authors and Affiliations

Sovaila S ^*

de Raigniac A ^*

Picard C ^**

Taulera O ^*

Lascoux-Combe C ^*

Sereni D ^*

Bourgarit A ^*

* *Department of Internal Medicine, Saint-Louis Hospital, AP-HP, Paris Denis-Diderot University, Paris, France

** **Department of Respiratory Medicine, Saint-Louis Hospital, AP-HP, Paris Denis-Diderot University, Paris, France

Correspondence to:Dr Anne Bourgarit, Internal Medicine Department, Hautepierre Hospital, Avenue Moliere, 67000 Strasbourg, France Phone: +33 3 88 12 75 94, Fax: +33 3 88 12 75 96; E-mail: anne.bourgarit-durand@chru-strasbourg.fr

Abstract

Highly active antiretroviral therapy for AIDS sometimes engenders inflammatory manifestations resulting from an inappropriate and unbalanced immune-system restoration, called Immune Reconstitution inflammatory Syndrome, which, in turn, can unmask a subclinical infection/pathology. Despite our patient’s evident syndrome, the atypical clinical, microbiologic and radiologic feature of Pneumocystis pneumonia made its diagnosis difficult.

Keywords

immune restoration inflammatory syndrome (IRIS)Pneumocystis jiroveciHIVunmaskingHAART

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About this article

PMC ID: 3391890
PubMed ID: 22802889
DOI:

Article Publishing Date (print): 12-06-2012
Available Online: 18-06-2012

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.