Multiresistance to antibiotics of Salmonella enterica serovar Typhimurium strains producing extended spectrum beta-lactamases (ESBLs) • JML Journal of Medicine and Life

2014, Volume 7, Issue Spec Iss 2, pp 80 – 82

Multiresistance to antibiotics of Salmonella enterica serovar Typhimurium strains producing extended spectrum beta-lactamases (ESBLs)

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Authors and Affiliations

Coculescu BI ^*

Palade AM ^**

Purcarea VL ^***

* *“Titu Maiorescu” University, Faculty of Medicine, Bucharest

** **”Cantacuzino” National Institute for Research and Development in Microbiology and Immunology, Bucharest

*** ***“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Bucharest

Correspondence to:Coculescu Bogdan-Ioan, MD, PhD “Titu Maiorescu” University, Bucharest, Romania, 22 Dambovnicului Street, code 040441, Bucharest Phone: 021 316 1646, E-mail: bogdancoculescu@yahoo.fr

Abstract

The purpose of the study is to give the rising incidence of Salmonellosis and the continuous decrease of sensitivity of Salmonella to a range of antibiotics, the prime importance of the choice of optimal anti-infective chemotherapy in order to prevent the selection of multidrug-resistant strains (MDR). We have studied 54 strains of Salmonella sent for further investigation to “Cantacuzino” NIRDMI Bucharest. The statistical analysis was based on the interpretation pathogen susceptibility and analyzed according to CLSI recommendations 2009, which revealed that 8 (14,81%) identified as S. enterica serovar Typhimurium group, presented a phenomenon of MDR. S. Typhimurium strains producing ESBL showed resistance mechanisms associated with beta-lactam resistance to aminoglycosides, quinolones, sulfonamides and tetracyclines.

Keywords

Salmonella enterica serovar TyphimuriumESBL (extended spectrum beta-lactamase))multidrug-resistant strains (MDR)

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About this article

PMC ID: 4391345
PubMed ID: 25870680
DOI:

Article Publishing Date (print): 2014
Available Online:

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.