2023, Volume 16, Issue 3, pp 341 – 343

125 years of the Wertheim operation. What next?

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Corresponding Author: Emmanuel Drouin, Neurology Service, Lille Catholic Institute Hospital Group, Lomme cedex, France. E-mail: emmanuel.drouin@univ-catholille.fr

Abstract

The Austrian gynecologist Ernst Wertheim (1864-1920) was a pioneer in the surgical treatment of cancer. The principle of Wertheim’s hysterectomy was to remove the uterus and the cervix with appropriate parametrium and tissues surrounding the upper vagina and pelvic lymph nodes. However, in the early 2000s, a meta-analysis of randomized trials revealed that radiotherapy and concomitant chemotherapy without surgical removal of the uterus were more effective in the historical treatment of advanced cervical cancer. This finding challenged the use of radical abdominal hysterectomy (RAH) in such cases and demonstrated the superiority of radiotherapy and chemotherapy in terms of overall survival.

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About this article

PMC ID: 10165519
PubMed ID: 37168301
DOI: 10.25122/jml-2022-0082

Article Publishing Date (print): 3 2023
Available Online: 

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


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