MALT lymphoma: epidemiology, clinical diagnosis and treatment • JML Journal of Medicine and Life

2018, Volume 11, Issue 3, pp 187 – 193

MALT lymphoma: epidemiology, clinical diagnosis and treatment

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Authors and Affiliations

Violeta Filip Petruta ^{¹ ²}

Cuciureanu Denisa ^¹

Sorina Diaconu Laura ^{¹ ²}

Maria Vladareanu Ana ^{¹ ²}

Silvia Pop Corina ^¹

1. 1.“Carol Davila” University of Medicine and Pharmacy, Bucharest

2. 2.Department of Internal Medicine II and Gastroenterology, Emergency University Hospital, Bucharest

Corresponding Author: Laura Sorina Diaconu, MD, PhD Specialist in Internal Medicine and Gastroenterology Street Splaiul Independentei no 169, sector 5, Bucharest, Romania Phone: +40744481170

Abstract

Primary gastric lymphoma (PGL) represents a rare pathology, which can be easily misdiagnosed because of unspecific symptoms of the digestive tract. Histologically, PGL can vary from indolent marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) to aggressive diffuse large B-cell lymphoma (DLBCL). During the years, clinical trials revealed the important role of Helicobacter pylori (H. pylori) in the pathogenesis of gastric MALT lymphoma. Infection with Helicobacter pylori is an influential promoter of gastric lymphomagenesis initiation. Long-term studies revealed that eradication therapy could regress gastric lymphomas.

Keywords

gastric lymphomaHelicobacter pylorimucosa-associated lymphoid tissue lymphomadiffuse large B-cell lymphoma

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About this article

PMC ID: 6197515
PubMed ID: 30364585
DOI: 10.25122/jml-2018-0035

Article Publishing Date (print): Jul-Sep 2018
Available Online:

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.