Diagnosis and treatment challenges in a patient with splenic tumor and chronic viral hepatitis • JML Journal of Medicine and Life

2015, Volume 8, Issue 4, pp 467 – 470

Diagnosis and treatment challenges in a patient with splenic tumor and chronic viral hepatitis

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Authors and Affiliations

Firulescu SC ^*

Săndulescu DL ^**

Dinescu ŞC ^*

Gheonea IA ^***

Purcarea RM ^****

Săndulescu SM ^*****

* *Department of Internal Medicine, Emergency County Hospital Craiova, Romania

** **Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania

*** ***Radiology and Imaging Department, University of Medicine and Pharmacy Craiova, Romania

**** ****”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; "Dr. Carol Davila" Clinical Hospital of Nephrology, Bucharest, Romania

***** *****Surgery Department, Emergency County Hospital Craiova, Romania

Correspondence to: Daniela Larisa Săndulescu, MD University of Medicine and Pharmacy Craiova, Romania, Research Center of Gastroenterology and Hepatology 2 Petru Rares Street, Craiova, Romania Mobile phone: +40723 968 354, Fax: +40251 310 287, E-mail: larisasandulescu@yahoo.com

Abstract

Non-Hodgkin lymphoma is a cancer of the lymphatic tissue located in various parts of the body: lymph nodes, spleen, thymus, adenoids, tonsils, and bone marrow. The disease occurs mainly in adults, with a higher incidence within the age range of 45 to 60 years. We present a clinical case of non-Hodgkin lymphoma diagnosed in a patient with chronic viral hepatitis B and D. The particularity of this case consists in the diagnosis of primitive spleen lymphoma, described in less than 1% of the cases, and also the difficult antiviral therapy recommendation for the liver disease, given the associated co-morbidity.

Abbreviations: NHL = Non-Hodgkin lymphoma, HDV = Hepatitis delta virus, HCV = Hepatitis C virus, HBV = Hepatitis B virus, CT = Computerized tomography, CEUS = Contrast enhanced ultrasonography, CHOP = cyclophosphamide, doxorubicin, vincristine, prednisone, R-CHOP = cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab

Keywords

non-Hodgkin’s lymphomadelta hepatitiscontrast enhanced ultrasoundsplenic tumor

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JMedLife-08-467

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About this article

PMC ID: 4656954
PubMed ID: 26664472
DOI:

Article Publishing Date (print): Oct-Dec 2015
Available Online:

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.