2015, Volume 8, Issue 1, pp 99 – 102

Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds

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Authors and Affiliations

Correspondence to:Gradinaru S, MD Ophthalmology Department, “Carol Davila” University of Medicine and Pharmacy 8 Eroilor Sanitari Blvd., Bucharest, Romania, Mobile phone: +40 726 535 515, E-mail: sanzinic@yahoo.com

Abstract

Introduction: This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.

Materials and Methods: the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus – rabbit) between August and November 2014, at “Carol Davila” University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.

Results: The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.

Conclusions: The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.

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About this article

PMC ID: 4397532
PubMed ID: 25914749
DOI: 

Article Publishing Date (print): Jan-Mar 2015
Available Online: 

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


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