Morphohistochemical alterations of neurons of the supraoptic nucleus of the rat hypothalamus at different durations of the photoperiod and melatonin administration • JML Journal of Medicine and Life

2021, Volume 14, Issue 6, pp 810 – 815

Morphohistochemical alterations of neurons of the supraoptic nucleus of the rat hypothalamus at different durations of the photoperiod and melatonin administration

Issues

Special Issues

Authors and Affiliations

Bulyk Roman Yevgenovych ¹

Smetanyuk Oleksiy Vasyliovych ¹

Vlasova Kateryna Vasylivna ¹

Kryvchanska Mariana Ivanivna ¹

Yosypenko Vladyslav Romanovych ¹

Voloshyn Volodymyr Leonidovych ¹

Tymchuk Kateryna Yuriivna ¹

Bulyk Tetyana Sergiivna ²

Rynzhuk Larysa Vasylivna ²

Sheremet Michael Ivanovych ³

Proniaiev Dmytro Volodymyrovych ⁴

1. Department of Medical Biology and Genetics, Bukovinian State Medical University, Chernivtsi, Ukraine

2. Department of Obstetrics and Gynecology, Bukovinian State Medical University, Chernivtsi, Ukraine

3. Surgery Department No.1, Bukovinian State Medical University, Chernivtsi, Ukraine

4. Department of Anatomy, Clinical Anatomy and Operative Surgery, Bukovinian State Medical University, Chernivtsi, Ukraine

*Corresponding Author: Michael Ivanovych Sheremet, MD, Ph.D., Associate Professor, Surgery Department No.1, Bukovinian State Medical University, Chernivtsi, Ukraine. E-mail: Mihayl71@gmail.com

Abstract

We studied the morphologic and histochemical organization of neurons of the hypothalamic supraoptic nucleus in rats exposed to different durations of photoperiod and injection of melatonin. Morphometric and histochemical analyses of neurons were performed after staining brain histological sections for RNA. Prolonged illumination leads to more pronounced changes in the parameters of hypothalamic structures at 2 a.m. than at 2 p.m., particularly decreasing the concentration of RNA in the cell nuclei. The use of exogenous melatonin does not normalize the revealed changes in the parameters of the studied structures of the neurons of the supraoptic nucleus of the hypothalamus caused by the prolonged stay of rats under conditions of constant illumination.

Keywords

hypothalamussupraoptic nucleusphotoperiodmelatonin

Preview

JMedLife-14-810

Download PDF

About this article

PMC ID: 8811669
PubMed ID: 35126752
DOI: 10.25122/jml-2021-0220

Article Publishing Date (print): Nov-Dec 2021
Available Online:

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.