2015, Volume 8, Issue 1, pp 75 – 78

Measuring the hepatic venous pressure gradient in the upper digestive hemorrhages

SCImago Journal & Country Rank

Issues

Special Issues

Authors and Affiliations

Correspondence to:Adrian Iftime, MD, PhD Department of Biophysics, ”Carol Davila” University of Medicine and Pharmacy, 8 Eroilor Sanitari Blvd., District 5, code 050474, Bucharest, Romania Phone: +4021 3180765, E-mail: iftime@adius.ro

Abstract

The upper digestive hemorrhage is one of the main causes of mortality from liver cirrhosis (CH). The measurement of the hepatic venous pressure gradient (HVPG) by angiographic way can be used for the determination of the risk of hemorrhage. The aim of this study is to verify the influence of the HVPG measurement upon the survival in patients with CH and upper digestive hemorrhage. A retrospective pilot study on 33 patients with upper digestive hemorrhage divided into two groups according to the therapeutic attitude followed, was carried out. One group was classically treated, with variceal band ligation, non-elective beta-blockers and in emergency Octreotide. The other group was treated depending on the value of HVPG. From the moment of the first episode of digestive hemorrhage, the survival period was in average of 8.1 months for the patients with viral etiology and for those with alcoholic etiology it was of 19.7 months. In patients treated after HVPG measurement, the average survival period was of 34.2 months and in patients “classically” treated, the average survival period was of 15.5 months (significant difference).

In conclusion, the measurement of HVPG allowed the selection of a high-risk group of patients. This permitted the making of a therapeutical decision with a significant prolongation of life in these patients.

Keywords

About this article

PMC ID: 4397526
PubMed ID: 25914744
DOI: 

Article Publishing Date (print): Jan-Mar 2015
Available Online: 

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


SCImago Journal & Country Rank

Issues

Special Issues