Clinical significance of HPV-DNA testing for precancerous cervical lesionS • JML Journal of Medicine and Life

2014, Volume 7, Issue Spec Iss 3, pp 37 – 39

Clinical significance of HPV-DNA testing for precancerous cervical lesionS

Issues

Special Issues

Authors and Affiliations

Moarcăs M ^*

Georgescu IC ^*

Brătilă E ^**

Badea M ^***

Cîrstoiu ECM ^*

* *Obstetrics and Gynaecology Department, University Emergency Hospital, Bucharest

** **Obstetrics and Gynaecology Department, “Sf. Pantelimon” Emergency Hospital

*** ***Micomi Clinic, Bucharest

Correspondence to:Mirela Moarcăs, MD, Primary Doctor Obstetrics and Gynaecology, University Emergency Hospital Bucharest, 169 Independenței Street, District 5, 050098, Bucharest, Romania, Mobile phone: 0723 322 758, E-mailː mirela.moarcas@yahoo.com

Abstract

Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV testing was proven most useful for women over 30 years old, in cases in which cytology identified ASC-US and after treatment for CIN. This article outlines the clinical significance of HPV-DNA testing for precancerous cervical lesions and the evidence that stands behind these recommendations.

Abbreviations: HPV = Human Papilloma Virus, ASC-US = Atypical Squamous Cells of Undetermined Significance, CIN = Cervical Intraepithelial Neoplasia, LSIL = Low Grade Squamous Intraepithelial Lesion, DNA = Deoxyribonucleic Acid

Keywords

HPVprecancerous cervical lesionsscreening

Preview

JMedLife-07-37

Download PDF

About this article

PMC ID: 4391422
PubMed ID: 25870692
DOI:

Article Publishing Date (print): 2014
Available Online:

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.