2010, Volume 3, Issue 4, pp 412 – 415

Deficiencies of Proteins C, S and Antithrombin and Activated Protein C Resistance–Their Involvement in the Occurrence of Arterial Thromboses

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Correspondence to:Angela Mirela Soare, Mobile phone:0722550555, email: drangelagavenea@yahoo.com

Abstract

Deficiencies of natural anticoagulants protein C, protein S, antithrombin and activated protein C resistance are components of inherited thrombophilia. Inherited thrombophilia was defined as a genetically determined tendency towards venous thromboembolism which characteristically occurs in young age (before 40 to 45 years) without apparent causes and tend to recur. In the recent years, there has been a lot of debate about the implication of these defects in arterial thromboses (peripheral artery disease, myocardial infarction, cerebral infarction). The screening for thrombophilia is recommended for young patients with spontaneous thromboses, arterial infarctions, family history of thromboses, personal history of recurrent abortions, with thrombosis of venous dural sinuses or strokes or myocardial infarctions, in patients with venous thrombosis at unusual sites, because the diagnosis of such a disease leads to a treatment that is lifesaving [1,2].

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About this article

PMC ID: 3019073
PubMed ID: 21254740
DOI: 

Article Publishing Date (print): 15-11-2010
Available Online: 25-11-2010

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.


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