Possibilities and limits in the treatment of congenital diaphragmatic hernia • JML Journal of Medicine and Life

2014, Volume 7, Issue 3, pp 433 – 439

Possibilities and limits in the treatment of congenital diaphragmatic hernia

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Authors and Affiliations

Georgescu R ^*

Chiuţu L ^**

Nemeş R ^*

Georgescu I ^*

Stoica A ^***

Georgescu E ^*

* *1st Surgical Clinic, Craiova University of Medicine and Pharmacy, Craiova, Romania

** **Intensive Care Unit, Craiova University of Medicine and Pharmacy, Craiova, Romania

*** ***Pediatric Surgical Clinic, Craiova University of Medicine and Pharmacy, Craiova, Romania

Correspondence to:Luminiţa Chiuţu, MD 12 Dimitrie Bolintineanu Street, Craiova, Dolj Mobile phone: +40 723 345 246, E-mail: luminita.chiutu@gmail.com

Abstract

Aim: to establish a therapeutic strategy that will improve the prognosis and increase the survival rate in congenital diaphragmatic hernia.

Material and method: 14 congenital diaphragmatic hernias (incidence 1/1597 live births, 12 boys and 2 girls with a sex ratio of 6/1, 10 term infants and 4 preterm first degree, 11 natural births and 3 by caesarean section) admitted to the Clinic of Pediatric Surgery Craiova, in a 5-year period (2007-2012), were analyzed from the therapeutic point of view. The “tension free” primary suture was the main surgical procedure to repair the diaphragmatic defect in all cases, preceded by a period of preoperative resuscitation and stabilization (2.8 days on average).

Results: We registered a survival rate of 64.29% and a postoperative mortality rate of 35.71%.

Conclusions: delayed surgery preceded by a period of the preoperative respiratory resuscitation and stabilization (24-72 hours on average) significantly reduced postoperative mortality and increased the survival rate.

Keywords

congenital diaphragmatic herniasmalformationsdiaphragm embryogenesisconventional mechanical ventilationprenatal diagnosis

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About this article

PMC ID: 4233455
PubMed ID: 25408771
DOI:

Article Publishing Date (print): 15-09-2014
Available Online: 25-09-2014

Journal information

ISSN Printing: 1844-122X
ISSN Online: 1844-3117
Journal Title: Journal of Medicine and Life

Copyright License: Open Access

This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.